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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49917ad4d44fdf13dbbbb2e6657caefbd34094587c11627b6adcb0caf1583095' 
  AND token = 'dTd4n3Rkkf3wnGdEGH8Iv7vBGpRQSaemrcS0H+CYUOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}