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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '442221fcc5dbb8f5d9bff1d13966cd14b07cbccd9d1e5a5d4dee8c6cef910d6c' 
  AND token = '18VpGvP6dsjlpeV8KYL3LtkjuonGouRJqUBrAcGR+dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}