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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b6e1fd5c8f4a25c377a17b561b38ea7fc6bf91d69adc6589804fbc08b47361f' 
  AND token = 'yXhHUoZbrP77Fk6/SGZcI0iWZr+/MOEj2wl7Yf9WL6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}