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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0544ebf16ee8847d0a435e675f52d028f5e10de6c80fad2675d86f1a33eff5a8' 
  AND token = '21liBczYClLII5WSllEqtkfjhOSni8aU3PsZLsBOkBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}