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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f6cd9653e62423d27cbfd53a4fb0778dcd531e44e51faead654ea2d0bad6a23' 
  AND token = 'GyOsy5pCgzo0+LD8gXN5vbDGrjkWIsy+KJJAwbcqy9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}