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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1d748c769032d91ebdbe32fb9502c41b9123a4bc2cb718021df4441b3a3eb0' 
  AND token = 'xZ3azbRn0Kngw4aLsyr8nRkwJEPmf1cQLJf8A1t+sx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}