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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23eb0adb110a19000a8e7c1459efb9d74f9d02d1d274e5f1f5dda5aeb0b6ec48' 
  AND token = '2RScilMecWGT5GtfkgDydS3mTcwB3DPOh61C+VtljaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}