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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16bb5f3360b1d94493c1c0a18a38e075f29316541f0b3c6a1ffede381564e63f' 
  AND token = 'BKr9+DPyVmI1La21GEtWNy22QH7hLdgjBvgFXey1koc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}