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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81c2e3acf4b864d1992ed50c70f0f90def5dadf435ee50bed09f494f783a246' 
  AND token = '7/LtbF3w0Ki63orGboF1WCvQYxjZAv22S7mihvKovoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}