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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d8bcfaad50a6425daa053fe44567840df6e6eb4846f51ade631d76bab9b043' 
  AND token = 'z3SKOAoesXZTJsqqGJ0UGe7yO5clYGM+4jeMf0hr9Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}