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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb1a4d10a6e91188f3399b7075a01840ce2465a1f76fead8cc106f338c7df7b0' 
  AND token = 'VJP7k+eIcotg3BNZJh526opNPveEKpZoBiFVIklh30s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}