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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '717daa33da9bbe0b6be0e278b7ebf930d5928a0ee1617e8f4232f90481a90b51' 
  AND token = 'Uxlxfe4RFnl0QcCh+f0Q99a8GTuTwte79ZmAIVRy8Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}