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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '529c1cd505c3ba20f9bc10bd0809e4c091d728a4164dd225870156388573c8f0' 
  AND token = 'XZN+t+MpW3Xm1omp7Uz/js+9rGM+J1ckFw3BafBYaqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}