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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458a0078773f113090730b71a51d03e7353a8a48e87e348ec0b48a2e6d15e6c6' 
  AND token = '5pjJMjRwPmO8B4SdXDscoUxtGX+PM65UXqwn8tiVdTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}