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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d0404a30ee4329b8d41e38892213c9347f5b294923d420ef45b3c5a766cbc7' 
  AND token = 'obfFIp2nzMGQ79psNpbgwalG6ugtkMGWu0sgpx62XrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}