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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de55f30352c54c395a00cfa80ed39af9a314b612a429c441bf7cdd62c9cd118f' 
  AND token = '+RsI6zlp4TgwtyJW7m7ngeMJmfv2A/ElY1euTt4YzM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}