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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6526be8163a2857a994a2b9fae02487d3660c9179e1a7a00f29301055aa0de00' 
  AND token = 'ItoGup1ST+uebJ6pMA1Cey4tQSk8JgNtKVs36ssAfsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}