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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449e6362e246ff967dcc817b4678566fcdb976aa8a5d2d21c754bc93c6c8658a' 
  AND token = 'Ds+GWIF7bfMwUX6ByTPYnbX3mZ7AO8b8FMRymv4hEII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}