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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461fd9b72c8f02c0f681f5e4c48f83299e5b049ee999c5dd9de5bb9e609f4f60' 
  AND token = 'OvJ/uWOJNnSOFWDy/ezpxoKnWVtr2yewuFaZKrpNz7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}