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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '525b446b49feec1278cc3711919f03f60f9bf04b6cb9359515f1c8ffb9ffc276' 
  AND token = 'zEcc4uAe5/vFxAL4cUf+aDnzTO88RDtF6ue+DY6BbgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}