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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d9286a64e99fd3a3c1cab201130481853c80a9dc8f628fbb9a089dff3214b5' 
  AND token = '54B2Mo0qy3crgndqiqdtJavKfN57elRABW7DCrzOr0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}