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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7c9d252c205358e08fd2c598699e4dd27da18da5a7195fea03c5542fd0077c0' 
  AND token = 'qnKb55sPwAznj20C1aTxFiI04I35BBWlYUdolmHr05M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}