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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d7ad0d13f72c8d36e759c3cf51ac46e5b4fccf486e7e204d052f93642d00be' 
  AND token = 'O72EBCbKsXlzoN8De84yesiVIOqNSbH21aon6xHCvRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}