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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f65492d0e8a162584fe7c444777cc9de5fe0dc97850d40336bdcf8da7d2e5ee4' 
  AND token = 'o2Cfe0mbpgZr8jlbrpVywQuWHu/mMLC4nS2+WcWH1vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}