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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744cc01df747d8a61820d1637e2762922f0b7e2973a78fb381af0c31176e16df' 
  AND token = 'bmLQ23CBzzggiIDMfo5XAyMdW4mHghYqBLW4/V4qfhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}