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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4266f635583b172e0d6d32bdbcf72b9b8fc9574c5b3784e5983e136043edaeda' 
  AND token = '4jn+BPQQRMKf59uSBn8BKNBo9XpxrFtQWbcWLfxs8wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}