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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9981c17a71df20c8db07b185722777a9bb822fdfc4e9ab6b430954fae19c3b2e' 
  AND token = 'laB/Lp4AYf06H7nCiwTI2jD94yJTAll0LmjHag2bqTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}