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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ee78119a805754f312863ba2f8ff6d4a845b3a363b5285834ac7d6bad99289' 
  AND token = 'xXEO4LlUwG629+a56RK5bPtD8u45ytRkktM2VB20btE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}