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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161d5c79fd3bfa2e3565a0b94bc02ce86a615b6e300182ad88e167d283aa4f32' 
  AND token = 'hM+7gQjqw8a15Od2ueSkAK1IeNCQs2WtlNtL525FPo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}