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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d7351309b76cdaa7a86cd9ce028d9b07f85725f93fc552c156360c5bd9cd5e' 
  AND token = 'sAq+n+e92kDplJMMqFBFuAFWDD4GbPQmAxtHh8NcQ2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}