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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca291c0dfc8b55e9998cc813378069ad9de67c590734c25e2e8d834453b6e851' 
  AND token = 'S9IObOpiCT4q23CJPNxfG1dHV3jstHoPzN9++VY7MpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}