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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae1463cf809c8f60b18f6d05f7bc221b036cb328dabb7f84f9fc3f61dd0ec73' 
  AND token = 'hyaD0RIql4DVWdZeZcc3wTj1SxKIzrYK0h2UK5kdUg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}