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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0ea5d8c9c8de2c0d51998b88c71ac546a692462b51135b4ae9d815a21da4e0' 
  AND token = 'RlqJBY5p3+e1GhsVh75mBsYtsVHJDmHqwwiP4A0Uv3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}