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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f13be649cc3356eace02f6d0c2b57c84e40f7d725ad56b71518d57d3309f43' 
  AND token = 'z568iywz9r8lM6385RD/0rmHqK/I7bwHGMsnd+nhW6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}