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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8fdb398e3459f14188db0b331ec3272eb1d88af8394bf828dfe4242984cc4bc' 
  AND token = '+k4FYR+t8Uj4MyQ12FeqeRyeZbpN6t3B/iUjbXcg/yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}