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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73900f416a52a7f99e680659dcbc9b53a8194151b98bc8ac3d5fc63b063314f4' 
  AND token = 'Em3OXQzuIOguhxU9Js/TCZztZ2cU+HQeeJ8Qr0WT4Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}