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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19110aefa9c96a78307e1698589a43d3e43eaa4c0e00f0f22da304a5ed66b10d' 
  AND token = 'B4bMx2cnoYEAIQ/knGr4AB+befdCTVFwzAeKFjpD5JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}